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Side Effects of EDTA-2Na

03/02/2016 admin

Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is an aminopolycarboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA.

 

General Side Effects

No significant side effects reported.

 

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Official Suggested Dosage

ADI: 0-2.5 mg/kg bw (Acceptable Daily Intake)

MTDI: None (Maximum Tolerable Daily Intake)

Data Source: JECFA Database of WHO

 

EDTA-2Na is widely known as safe, there is no limit on dosage of intake. There is no proof showing that acquiring EDTA-2Na will do any harm to special groups, including newborns, children, pregnant, and other applicable vulnerable groups. It should be safe to use EDTA-2Na in food and beverages as a food additive without any side effects. However, we still recommend consumers to consult food ingredient experts before using large quantity of EDTA-2Na for long period of time. There may be some side effects in large dosage.

 

GRAS (Generally Recognized as Safe) Substances

Yes. EDTA-2Na is not on FDA’s GRAS exemption list, it’s widely accepted and used as a safe food ingredient in many countries.

 

Sources and Related Researches:

https://en.wikipedia.org/wiki/Ethylenediaminetetraacetic_acid

http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=385

http://pubchem.ncbi.nlm.nih.gov/compound/13020083

http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm?cfrpart=172