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Side Effects of Sodium Carboxymethyl Cellulose

03/04/2016 admin

Carboxymethyl cellulose (CMC) or cellulose gum is a cellulose derivative with carboxymethyl groups bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone. It is often used as its sodium salt, sodium carboxymethyl cellulose. It is synthesized by the alkali-catalyzed reaction of cellulose with chloroacetic acid. The polar (organic acid) carboxyl groups render the cellulose soluble and chemically reactive.

 

General Side Effects

No significant side effects reported.

 

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Official Suggested Dosage

ADI: NOT SPECIFIED (Acceptable Daily Intake)

MTDI: None (Maximum Tolerable Daily Intake)

Data Source: JECFA Database of WHO

 

Sodium Carboxymethyl Cellulose is widely known as safe, there is no limit on dosage of intake. There is no proof showing that acquiring Sodium Carboxymethyl Cellulose will do any harm to special groups, including newborns, children, pregnant, and other applicable vulnerable groups. It should be safe to use Sodium Carboxymethyl Cellulose in food and beverages as a food additive without any side effects. However, we still recommend consumers to consult food ingredient experts before using large quantity of Sodium Carboxymethyl Cellulose for long period of time. There may be some side effects in large dosage.

 

GRAS (Generally Recognized as Safe) Substances

Yes. Sodium Carboxymethyl Cellulose is on FDA’s GRAS exemption list, it’s widely accepted and used as a safe food ingredient in many countries.

 

Sources and Related Researches:

https://en.wikipedia.org/wiki/Carboxymethyl_cellulose

http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=3773

http://pubchem.ncbi.nlm.nih.gov/compound/23706213

http://www.fda.gov/food/ingredientspackaginglabeling/gras/scogs/ucm261244.htm