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Side Effects of L-Leucine

04/05/2016 admin

Properties: White crystalline powder; taste slightly bitterMelting point 293 ~ 295 (decomposition). Dissolved in 40ml of water per gram of acetic acid and about 100ml. Slightly soluble in ethanol, soluble in diluted hydrochloric acid and alkali hydroxide and carbonate solution. Uses: Nutritional supplements. Generally used for bread, flour products. The preparation of amino acid infusion and a comprehensive amino acid preparations, hypoglycemic agents, plant growth promoters. 


General Side Effects

No significant side effects reported.


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Official Suggested Dosage

ADI: NOT LIMITED (Acceptable Daily Intake)

MTDI: NOT LIMITED (Maximum Tolerable Daily Intake)

Data Source: JECFA Database of WHO


L-Leucine is widely known as safe, there is no limit on dosage of intake. There is no proof showing that acquiring L-Leucine will do any harm to special groups, including newborns, children, pregnant, and other applicable vulnerable groups. It should be safe to use L-Leucine in food and beverages as a food additive without any side effects. However, we still recommend consumers to consult food ingredient experts before using large quantity of L-Leucine for long period of time. There may be some side effects in large dosage.


GRAS (Generally Recognized as Safe) Substances

Yes. L-Leucine is on FDAs GRAS exemption list, its widely accepted and used as a safe food ingredient in many countries.


Sources and Related Researches:

https://en.wikipedia.org/wiki/Citric_acid https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1033 http://pubchem.ncbi.nlm.nih.gov/compound/citric_acid