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Side Effects of Polysorbate 60

04/07/2016 admin

The Polysorbate 60 (Tween-60, TW 60) is a multi-functional ionic hydrophilic surfactant often blended with Sorbitans such as SP20, SP60 or SP80 and SP80K non-ionic lipophilic surfactants to achieve optimal HLB values.

In general Polysorbates or Tweens are ionic hydrophilic surfactants used as emulsifying agents in the preparation of vaccines, creams and ointments for pharmaceutical and cosmetics and in food products.


General Side Effects

No significant side effects reported.


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Official Suggested Dosage

ADI: NOT LIMITED (Acceptable Daily Intake)

MTDI: NOT LIMITED (Maximum Tolerable Daily Intake)

Data Source: JECFA Database of WHO


Polysorbate 60 is widely known as safe, there is no limit on dosage of intake. There is no proof showing that acquiring Polysorbate 60 will do any harm to special groups, including newborns, children, pregnant, and other applicable vulnerable groups. It should be safe to use Polysorbate 60 in food and beverages as a food additive without any side effects. However, we still recommend consumers to consult food ingredient experts before using large quantity of Polysorbate 60 for long period of time. There may be some side effects in large dosage.


GRAS (Generally Recognized as Safe) Substances

Yes. Polysorbate 60 is on FDA’s GRAS exemption list, it’s widely accepted and used as a safe food ingredient in many countries.


Sources and Related Researches:

https://en.wikipedia.org/wiki/Citric_acid https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1033 http://pubchem.ncbi.nlm.nih.gov/compound/citric_acid